topics / anti-doping

Tagged anti-doping.

10/10 · Established Anastrozole (Arimidex) Anastrozole is a non-steroidal aromatase inhibitor — a prescription breast-cancer drug, not a peptide — with strong trial evidence in postmenopausal women and a separate, unstudied off-label use by men to suppress estrogen. It is banned in sport at all times.
7/10 · Moderate Clenbuterol Clenbuterol is a long-acting beta-2 adrenergic agonist (a bronchodilator and livestock 'repartitioning' agent) used off-label for fat loss — never FDA-approved for humans, banned in sport as an anabolic agent, and notable for serious cardiac and electrolyte toxicity. It is not a steroid and not a peptide.
8/10 · Good Enclomiphene Enclomiphene is the anti-estrogenic isomer of clomiphene — a selective estrogen receptor modulator (SERM), not a peptide. Human trials consistently show it raises testosterone while preserving fertility, but it is NOT FDA-approved for any use, is available only via off-label compounding, and is banned in sport at all times.
10/10 · Established Exemestane (Aromasin) Exemestane is an oral, steroidal third-generation aromatase inhibitor — an FDA-approved breast-cancer drug, not a peptide. Bodybuilders use it off-label to suppress estrogen, an unapproved and unstudied practice that is banned in sport (WADA S4) and can be genuinely harmful when estrogen is crashed.
6/10 · Preliminary Follistatin 344 A myostatin/activin-pathway antagonist that is biologically real but clinically unproven; its only legitimate human testing was tiny early-phase gene therapy in muscular dystrophy, with no human evidence for muscle-building or weight loss, no regulatory approval, and a permanent WADA ban.
10/10 · Established Insulin Insulin is a 51-amino-acid peptide hormone and one of medicine's most life-saving drugs for diabetes — but as a performance/anabolic agent in healthy people it has no good efficacy evidence and the highest acute lethality risk of common PEDs.
10/10 · Established Letrozole (Femara) Letrozole is an oral, nonsteroidal third-generation aromatase inhibitor — an FDA-approved breast-cancer and (off-label) fertility drug, not a peptide. Bodybuilders use it off-label to suppress estrogen, an unapproved and unstudied practice that is banned in sport (WADA S4) and can be genuinely harmful when estrogen is crashed.
7/10 · Moderate Ostarine (MK-2866) Ostarine is an investigational selective androgen receptor modulator (SARM) — not a peptide — with real but limited human evidence for lean-mass effects, no regulatory approval anywhere, and documented liver-injury and hormone-suppression signals.
10/10 · Established Raloxifene (Evista) Raloxifene is a selective estrogen receptor modulator (SERM) — an FDA-approved postmenopausal osteoporosis and breast-cancer-risk-reduction drug, not a peptide. Its defining serious risks are blood clots and fatal stroke; it is banned in sport at all times (WADA S4.2).
10/10 · Established Tamoxifen (Nolvadex) Tamoxifen is a selective estrogen receptor modulator (SERM) — an FDA-approved breast-cancer drug with one of the strongest evidence bases in oncology, not a peptide. Anabolic-steroid users take it off-label to blunt gynecomastia and attempt testosterone 'restart,' an unstudied practice that is banned in sport (WADA S4.2) and not without real risk.
7/10 · Moderate Tesofensine Tesofensine is an investigational oral triple monoamine (noradrenaline/dopamine/serotonin) reuptake inhibitor studied for obesity. It is a small molecule, not a peptide, and is not approved by any major regulator. It is banned in sport as a stimulant.
10/10 · Established Testosterone Testosterone is the principal human androgen and the prototypical anabolic-androgenic steroid (AAS) — not a peptide — with strong, reproducible human evidence for dose-dependent muscle and strength gains, FDA approval only for confirmed hypogonadism, Schedule III control, and real cardiovascular, hematologic, and hormonal safety signals.
3/10 · Animal only Trenbolone Trenbolone is a potent injectable anabolic-androgenic steroid — never a peptide — with no human efficacy trials, an FDA-approved use only as a cattle growth-promoting implant, and serious androgenic, cardiovascular, and hormonal risks.